G Michael Felker Selected Research

Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)

1/2022	Worsening renal function in acute heart failure in the context of diuretic response.
1/2021	The lower is not always the better: a more comprehensive understanding of loop diuretics in heart failure.
1/2020	Diuretic Therapy for Patients With Heart Failure: JACC State-of-the-Art Review.
1/2019	Spironolactone in Acute Heart Failure Patients With Renal Dysfunction and Risk Factors for Diuretic Resistance: From the ATHENA-HF Trial.
1/2018	Worsening Renal Function in Patients With Acute Heart Failure Undergoing Aggressive Diuresis Is Not Associated With Tubular Injury.
1/2016	Rationale and Design of the ATHENA-HF Trial: Aldosterone Targeted Neurohormonal Combined With Natriuresis Therapy in Heart Failure.
1/2016	Intensification of Medication Therapy for Cardiorenal Syndrome in Acute Decompensated Heart Failure.
11/2014	Diuretic response in patients with acute decompensated heart failure: characteristics and clinical outcome--an analysis from RELAX-AHF.
10/2014	Fluid removal in acute heart failure: diuretics versus devices.
2/2013	Approaches to decongestion in patients with acute decompensated heart failure.

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G Michael Felker Research Topics

Disease

229	Heart Failure 05/2022 - 01/2003
18	Renal Insufficiency (Renal Failure) 01/2020 - 09/2004
15	Dyspnea (Shortness of Breath) 01/2019 - 01/2010
14	Cardiomyopathies (Cardiomyopathy) 01/2021 - 03/2003
10	Atrial Fibrillation 01/2022 - 02/2007
10	Inflammation (Inflammations) 08/2020 - 11/2006
8	Weight Loss (Weight Reduction) 01/2022 - 12/2012
7	Heart Diseases (Heart Disease) 03/2021 - 10/2013
7	Anemia 06/2017 - 09/2003
5	Diabetes Mellitus 01/2021 - 01/2017
5	Fibrosis (Cirrhosis) 01/2020 - 06/2014
4	Ventricular Remodeling 01/2021 - 03/2012
4	Systolic Heart Failure 01/2021 - 10/2014
4	Disease Progression 01/2021 - 03/2006
4	Body Weight (Weight, Body) 01/2019 - 12/2009
4	Stroke (Strokes) 08/2015 - 02/2010
3	Thrombosis (Thrombus) 01/2020 - 11/2011
3	Hypotension (Low Blood Pressure) 01/2020 - 04/2016
3	Obesity 01/2020 - 11/2012
3	Diastolic Heart Failure 01/2017 - 03/2015
3	Necrosis 01/2017 - 02/2014
3	Shock 01/2008 - 01/2004
2	Frailty 01/2022 - 02/2014
2	Myocardial Infarction 01/2022 - 02/2010
2	Type 2 Diabetes Mellitus (MODY) 01/2021 - 08/2016
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 01/2016
2	Acute Coronary Syndrome 11/2020 - 11/2012
2	Cardiac Sudden Death (Sudden Cardiac Arrest) 10/2020 - 06/2014
2	Left Ventricular Dysfunction 01/2020 - 01/2012
2	Pathologic Processes 01/2020 - 05/2017
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 01/2017
2	Cardiac Arrhythmias (Arrythmia) 01/2019 - 01/2008
2	Pulmonary Hypertension 09/2016 - 04/2002
2	Ventricular Dysfunction 03/2016 - 09/2006
2	Hypertension (High Blood Pressure) 03/2016 - 12/2009
2	Cardio-Renal Syndrome 01/2016 - 02/2015
2	Hyponatremia 09/2015 - 01/2012
2	Death (Near-Death Experience) 01/2015 - 06/2008
2	Hemolysis 02/2014 - 05/2013

Drug/Important Bio-Agent (IBA)

58	Biomarkers (Surrogate Marker)IBA 03/2022 - 02/2006
45	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2022 - 04/2009
33	DiureticsIBA 01/2022 - 12/2009
29	pro-brain natriuretic peptide (1-76)IBA 03/2022 - 10/2009
18	Natriuretic PeptidesIBA 01/2022 - 09/2006
18	Sodium Potassium Chloride Symporter Inhibitors (Loop Diuretics)IBA 01/2022 - 01/2009
12	omecamtiv mecarbilIBA 05/2022 - 03/2016
11	CreatinineIBA 01/2022 - 01/2012
11	RelaxinIBA 12/2021 - 04/2009
9	sacubitril and valsartan sodium hydrate drug combinationIBA 01/2021 - 09/2019
8	Cardiac MyosinsIBA 01/2022 - 03/2016
6	Type 5 Cyclic Nucleotide PhosphodiesterasesIBA 01/2020 - 03/2013
6	Milrinone (Primacor)FDA LinkGeneric 12/2006 - 01/2003
5	Biological ProductsIBA 01/2021 - 04/2002
5	Galectin 3 (LGALS3)IBA 01/2020 - 01/2012
5	TroponinIBA 12/2018 - 09/2010
5	Troponin T (Troponin T1)IBA 01/2016 - 12/2010
4	Mineralocorticoid Receptor AntagonistsIBA 01/2022 - 12/2009
4	Cystatin CIBA 01/2020 - 01/2013
3	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 01/2022 - 03/2004
3	Growth Differentiation Factor 15IBA 01/2021 - 11/2015
3	Glucagon-Like Peptide 1 (GLP 1)IBA 01/2021 - 08/2016
3	Liraglutide FDA Link 01/2021 - 08/2016
3	NitratesIBA 01/2020 - 10/2013
3	Spironolactone (Aldactone)FDA LinkGeneric 01/2019 - 01/2016
3	Troponin IIBA 12/2018 - 11/2012
3	LigandsIBA 02/2018 - 03/2015
3	Sildenafil Citrate (Viagra)FDA Link 01/2017 - 03/2015
3	C-Reactive ProteinIBA 05/2014 - 03/2004
3	Hemoglobins (Hemoglobin)IBA 02/2010 - 01/2006
2	Furosemide (Lasix)FDA LinkGeneric 01/2022 - 03/2011
2	Metformin (Glucophage)FDA LinkGeneric 01/2022 - 01/2022
2	Neprilysin (Neutral Endopeptidase)IBA 01/2021 - 01/2020
2	nitroxylIBA 01/2021 - 01/2019
2	Angiotensin Receptors (Angiotensin II Receptor)IBA 01/2021 - 03/2015
2	CytokinesIBA 01/2021 - 11/2006
2	Interleukin-6 (Interleukin 6)IBA 01/2021 - 11/2006
2	Myosins (Myosin)IBA 12/2020 - 12/2016
2	ReninIBA 01/2020 - 12/2019
2	AldosteroneIBA 01/2019 - 01/2016
2	Oxygen (Dioxygen)IBA 01/2019 - 01/2008
2	Sar-Arg-Val-Tyr-Ile-His-Pro-Ala-OHIBA 02/2018 - 03/2015
2	Type 1 Angiotensin ReceptorIBA 02/2018 - 08/2017
2	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2018 - 03/2013
2	IronIBA 05/2017 - 03/2010
2	Tolvaptan FDA Link 03/2017 - 09/2015
2	ElectrolytesIBA 04/2016 - 09/2015
2	coenzyme Q10 (CoQ10)IBA 04/2016 - 10/2010
2	CalciumIBA 03/2016 - 02/2014
2	Dopamine (Intropin)FDA LinkGeneric 01/2016 - 12/2013
2	Urea (Carbamide)FDA LinkGeneric 01/2015 - 02/2007

Therapy/Procedure

93	Therapeutics 03/2022 - 04/2002
21	Patient Readmission 01/2021 - 09/2003
13	Heart-Assist Devices 01/2020 - 01/2004
9	Length of Stay 01/2020 - 01/2010
7	Heart Transplantation (Grafting, Heart) 01/2020 - 11/2005
4	Transplantation 01/2015 - 01/2004
3	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 01/2021 - 01/2020
3	Intravenous Infusions 01/2019 - 01/2013
2	Investigational Therapies (Experimental Therapy) 11/2016 - 11/2015
2	Cutaneous Administration 03/2016 - 02/2014